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1

System approaches of Weiss and Bertalanffy and their relevance for systems biology today

Manfred Drack, Olaf Wolkenhauer

Journal:

Seminars in Cancer Biology

Année:

2011

Langue:

english

Fichier:

PDF, 246 KB

english, 2011

2

Encyclopedia of Systems Biology ||

Dubitzky, Werner, Wolkenhauer, Olaf, Cho, Kwang-Hyun, Yokota, Hiroki

Année:

2013

Langue:

english

Fichier:

PDF, 66.36 MB

english, 2013

3

An abstract cell model that describes the self-organization of cell function in living systems

Olaf Wolkenhauer, Jan-Hendrik S. Hofmeyr

Journal:

Journal of Theoretical Biology

Année:

2007

Langue:

english

Fichier:

PDF, 370 KB

english, 2007

4

Mathematical modelling in the post-genome era: understanding genome expression and regulation—a system theoretic approach

Olaf Wolkenhauer

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 380 KB

english, 2002

5

Encyclopedia of Systems Biology || Epigenetics, Drug Discovery

Dubitzky, Werner, Wolkenhauer, Olaf, Cho, Kwang-Hyun, Yokota, Hiroki

Année:

2013

Langue:

english

Fichier:

PDF, 2.57 MB

english, 2013

6

Encyclopedia of Systems Biology || Power-Law Functions

Dubitzky, Werner, Wolkenhauer, Olaf, Cho, Kwang-Hyun, Yokota, Hiroki

Année:

2013

Langue:

english

Fichier:

PDF, 4.02 MB

english, 2013

7

Diagnostic Potential of Imaging Flow Cytometry

Doan, Minh, Vorobjev, Ivan, Rees, Paul, Filby, Andrew, Wolkenhauer, Olaf, Goldfeld, Anne E., Lieberman, Judy, Barteneva, Natasha, Carpenter, Anne E., Hennig, Holger

Journal:

Trends in Biotechnology

Année:

2018

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2018

8

Evolution of computational models in BioModels Database and the Physiome Model Repository

Scharm, Martin, Gebhardt, Tom, Touré, Vasundra, Bagnacani, Andrea, Salehzadeh-Yazdi, Ali, Wolkenhauer, Olaf, Waltemath, Dagmar

Journal:

BMC Systems Biology

Année:

2018

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2018

9

Quick tips for creating effective and impactful biological pathways using the Systems Biology Graphical Notation

Touré, Vasundra, Le Novère, Nicolas, Waltemath, Dagmar, Wolkenhauer, Olaf, Ouellette, Francis

Journal:

PLoS Computational Biology

Année:

2018

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2018

10

Possibilistic testing of distribution functions for change detection

Olaf Wolkenhauer, John M. Edmunds

Journal:

Intelligent Data Analysis

Année:

1997

Langue:

english

Fichier:

PDF, 487 KB

english, 1997

11

Modeling the Calvin-Benson cycle

Jiri Jablonsky, Hermann Bauwe, Olaf Wolkenhauer

Journal:

BMC Systems Biology

Année:

2011

Langue:

english

Fichier:

PDF, 581 KB

english, 2011

12

Stochastic approaches in systems biology

Mukhtar Ullah, Olaf Wolkenhauer

Journal:

Wiley Interdisciplinary Reviews: Systems Biology and Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 227 KB

english, 2010

13

Investigating the two-moment characterisation of subcellular biochemical networks

Mukhtar Ullah, Olaf Wolkenhauer

Journal:

Journal of Theoretical Biology

Année:

2009

Langue:

english

Fichier:

PDF, 439 KB

english, 2009

14

Systems biology of JAK-STAT signalling in human malignancies

Julio Vera, Katja Rateitschak, Falko Lange, Christina Kossow, Olaf Wolkenhauer, Robert Jaster

Journal:

Progress in Biophysics and Molecular Biology

Année:

2011

Langue:

english

Fichier:

PDF, 863 KB

english, 2011

15

Feedback dynamics and cell function: Why systems biology is called Systems Biology

Wolkenhauer, Olaf, Mesarović, Mihajlo

Journal:

Molecular BioSystems

Année:

2005

Langue:

english

Fichier:

PDF, 123 KB

english, 2005

16

Systems Biology || All models are wrong ... some more than others

Wolkenhauer, Olaf

Année:

2007

Langue:

english

Fichier:

PDF, 428 KB

english, 2007

17

[Advances in Experimental Medicine and Biology] MicroRNA Cancer Regulation Volume 774 || MicroRNAs in Melanoma Biology

Schmitz, Ulf, Wolkenhauer, Olaf, Vera, Julio

Année:

2013

Langue:

english

Fichier:

PDF, 488 KB

english, 2013

18

Encyclopedia of Systems Biology || Agent-based Modeling

Dubitzky, Werner, Wolkenhauer, Olaf, Cho, Kwang-Hyun, Yokota, Hiroki

Année:

2013

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2013

19

Encyclopedia of Systems Biology || Molecular Marker

Dubitzky, Werner, Wolkenhauer, Olaf, Cho, Kwang-Hyun, Yokota, Hiroki

Année:

2013

Langue:

english

Fichier:

PDF, 9.15 MB

english, 2013

20

Gene Expression in Low- and High-Dose-Irradiated Human Peripheral Blood Lymphocytes: Possible Applications for Biodosimetry

Knops, Katja, Boldt, Sonja, Wolkenhauer, Olaf, Kriehuber, Ralf

Journal:

Radiation Research

Année:

2012

Langue:

english

Fichier:

PDF, 467 KB

english, 2012

21

Annotation-based feature extraction from sets of SBML models

Alm, Rebekka, Waltemath, Dagmar, Wolfien, Markus, Wolkenhauer, Olaf, Henkel, Ron

Journal:

Journal of Biomedical Semantics

Année:

2015

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2015

22

Encyclopedia of Systems Biology || Physiome Model Repository

Dubitzky, Werner, Wolkenhauer, Olaf, Cho, Kwang-Hyun, Yokota, Hiroki

Année:

2013

Langue:

english

Fichier:

PDF, 4.02 MB

english, 2013

23

[Methods in Molecular Biology] Systems Medicine Volume 1386 || Modeling and Simulation Tools: From Systems Biology to Systems Medicine

Schmitz, Ulf, Wolkenhauer, Olaf

Année:

2016

Langue:

english

Fichier:

PDF, 465 KB

english, 2016

24

Possibilistic Testing of Distribution Functions for Change Detection

Wolkenhauer, Olaf, Edmunds, John M.

Journal:

Intelligent Data Analysis

Année:

1997

Fichier:

PDF, 845 KB

1997

25

Bioinformatic assessment of mass spectrometric chemical derivatisation techniques for proteome database searching

Khushwant S. Sidhu, Polkit Sangvanich, Francesco L. Brancia, Anthony G. Sullivan, Simon J. Gaskell, Olaf Wolkenhauer, Stephen G. Oliver, Simon J. Hubbard

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2001

26

The curse of normalization

Olaf Wolkenhauer, Carla Möller-Levet, Fatima Sanchez-Cabo

Journal:

Comparative and Functional Genomics

Année:

2002

Langue:

english

Fichier:

PDF, 93 KB

english, 2002

27

Information-Theoretic Analysis of Protein Sequences Shows that Amino Acids Self-cluster

YUDONG CAI, C.T.J. DODSON, ANDREW J. DOIG, OLAF WOLKENHAUER

Journal:

Journal of Theoretical Biology

Année:

2002

Langue:

english

Fichier:

PDF, 408 KB

english, 2002

28

Optimal sampling time selection for parameter estimation in dynamic pathway modeling

Zoltán Kutalik, Kwang-Hyun Cho, Olaf Wolkenhauer

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 329 KB

english, 2004

29

A hybrid systems framework for cellular processes

Kwang-Hyun Cho, Karl Henrik Johansson, Olaf Wolkenhauer

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 342 KB

english, 2005

30

Dynamic properties of a delayed protein cross talk model

Svetoslav Nikolov, Julio Vera, Vladimir Kotev, Olaf Wolkenhauer, Valko Petrov

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2008

31

The role of dynamic stimulation pattern in the analysis of bistable intracellular networks

Thomas Millat, Sree N. Sreenath, Radina P. Soebiyanto, Jayant Avva, Kwang-Hyun Cho, Olaf Wolkenhauer

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 738 KB

english, 2008

32

A multi-level model accounting for the effects of JAK2-STAT5 signal modulation in erythropoiesis

Xin Lai, Svetoslav Nikolov, Olaf Wolkenhauer, Julio Vera

Journal:

Computational Biology and Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2009

33

How quantitative measures unravel design principles in multi-stage phosphorylation cascades

Simone Frey, Thomas Millat, Stefan Hohmann, Olaf Wolkenhauer

Journal:

Journal of Theoretical Biology

Année:

2008

Langue:

english

Fichier:

PDF, 444 KB

english, 2008

34

Nucleo-cytoplasmic shuttling of APC can maximize β‐catenin/TCF concentration

Yvonne Schmitz, Olaf Wolkenhauer, Katja Rateitschak

Journal:

Journal of Theoretical Biology

Année:

2011

Langue:

english

Fichier:

PDF, 667 KB

english, 2011

35

Identification of immunogenic consensus T-cell epitopes in globally distributed influenza-A H1N1 neuraminidase

Shishir K. Gupta, Mugdha Srivastava, Bashir A. Akhoon, Suchi Smita, Ulf Schmitz, Olaf Wolkenhauer, Julio Vera, Shailendra K. Gupta

Journal:

Infection, Genetics and Evolution

Année:

2011

Langue:

english

Fichier:

PDF, 968 KB

english, 2011

36

Computational analysis and modeling the effectiveness of ‘Zanamivir’ targeting neuraminidase protein in pandemic H1N1 strains

Shailendra K. Gupta, Shishir K. Gupta, Suchi Smita, Mugdha Srivastava, Xin Lai, Ulf Schmitz, Qamar Rahman, Olaf Wolkenhauer, Julio Vera

Journal:

Infection, Genetics and Evolution

Année:

2011

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2011

37

Level sets and minimum volume sets of probability density functions

Javier Nuñez Garcia, Zoltan Kutalik, Kwang-Hyun Cho, Olaf Wolkenhauer

Journal:

International Journal of Approximate Reasoning

Année:

2003

Langue:

english

Fichier:

PDF, 299 KB

english, 2003

38

A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture

Sylvia Haus, Sara Jabbari, Thomas Millat, Holger Janssen, Ralf-Jörg Fischer, Hubert Bahl, John R King, Olaf Wolkenhauer

Journal:

BMC Systems Biology

Année:

2011

Langue:

english

Fichier:

PDF, 658 KB

english, 2011

39

A stem cell niche dominance theorem

Olaf Wolkenhauer, Darryl K Shibata, Mihajlo D Mesarović

Journal:

BMC Systems Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2011

40

A model-based strategy to investigate the role ofmicroRNAregulation in cancer signalling networks

Svetoslav Nikolov, Julio Vera, Ulf Schmitz, Olaf Wolkenhauer

Journal:

Theory in Biosciences

Année:

2011

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2011

41

Thresholds in transient dynamics of signal transduction pathways

Katja Rateitschak, Olaf Wolkenhauer

Journal:

Journal of Theoretical Biology

Année:

2010

Langue:

english

Fichier:

PDF, 653 KB

english, 2010

42

How mathematical modelling elucidates signalling in Bacillus subtilis

Ulf W. Liebal, Thomas Millat, Imke G. De Jong, Oscar P. Kuipers, Uwe Völker, Olaf Wolkenhauer

Journal:

Molecular Microbiology

Année:

2010

Langue:

english

Fichier:

PDF, 425 KB

english, 2010

43

Stochastic Modeling for Systems Biology edited by D. J. Wilkinson

Olaf Wolkenhauer

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 102 KB

english, 2007

44

Power-law models of signal transduction pathways

Julio Vera, Eva Balsa-Canto, Peter Wellstead, Julio R. Banga, Olaf Wolkenhauer

Journal:

Cellular Signalling

Année:

2007

Langue:

english

Fichier:

PDF, 472 KB

english, 2007

45

Mathematical modelling of interferon-γ signalling in pancreatic stellate cells reflects and predicts the dynamics of STAT1 pathway activity

Katja Rateitschak, Anna Karger, Brit Fitzner, Falko Lange, Olaf Wolkenhauer, Robert Jaster

Journal:

Cellular Signalling

Année:

2010

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2010

46

The role of theorem proving in systems biology

Olaf Wolkenhauer, Darryl Shibata, Mihajlo D. Mesarović

Journal:

Journal of Theoretical Biology

Année:

2012

Langue:

english

Fichier:

PDF, 150 KB

english, 2012

47

Non-coding RNA detection methods combined to improve usability, reproducibility and precision

Peter Raasch, Ulf Schmitz, Nadja Patenge, Julio Vera, Bernd Kreikemeyer, Olaf Wolkenhauer

Journal:

BMC Bioinformatics

Année:

2010

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2010

48

The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells

Catrin Schult, Meike Dahlhaus, Sabine Ruck, Mandy Sawitzky, Francesca Amoroso, Sandra Lange, Daniela Etro, Aenne Glass, Georg Fuellen, Sonja Boldt, Olaf Wolkenhauer, Luca Maria Neri, Mathias Freund, C

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2010

49

Studies on mechanisms of interferon-gamma action in pancreatic cancer using a data-driven and model-based approach

Falko Lange, Katja Rateitschak, Brit Fitzner, Ralf Pöhland, Olaf Wolkenhauer, Robert Jaster

Journal:

Molecular Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 641 KB

english, 2011

50

A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway

Julio Vera, Julie Bachmann, Andrea C Pfeifer, Verena Becker, Jose A Hormiga, Nestor V Torres Darias, Jens Timmer, Ursula Klingmüller, Olaf Wolkenhauer

Journal:

BMC Systems Biology

Année:

2008

Langue:

english

Fichier:

PDF, 618 KB

english, 2008